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Intramolecular Photoelectrochemical System Using Tyrosine-Modified Antibody-Targeted Peptide as Electron Donor for Detection of Biomarkers

Shanghua Liu, Yue Jia, Hui Dong, Xiaodong Yu, Daopeng Zhang, Xiang Ren, Yueyun Li, Qin Wei

2020Analytical Chemistry27 citationsDOI

Abstract

heterojunction with a significant visible-light absorption is utilized as a photoelectric generator, and the motivation is ascribed to a proven proposition, namely, that short-wavelength illuminant radiates proteins, causing a decline in bioactivity of immune protein. An innovative biosensor is fabricated using the above strategies for the detection of CYFRA21-1, a biomarker of squamous cell lung carcinoma. This sort of PEC-based sensing platform shows convincing experimental data and could be an effective candidate for clinical application in the future due to their extremely skillful conception.

Topics & Concepts

ChemistryTyrosinePeptideBifunctionalIntramolecular forceNanotechnologyPhotochemistryBiochemistryStereochemistryCatalysisMaterials scienceAdvanced biosensing and bioanalysis techniquesAdvanced Photocatalysis TechniquesGa2O3 and related materials