The Phospha-Bora-Wittig Reaction
Andryj M. Borys, Ella F. Rice, Gary S. Nichol, Michael J. Cowley
Abstract
reacts with carbonyl compounds to form 1,2,3-phosphaboraoxetanes, analogues of oxaphosphetane intermediates in the classical Wittig reaction. 1,2,3-Phosphaboraoxetanes undergo thermal or Lewis acid-promoted cycloreversion, yielding phosphaalkenes. Experimental and density functional theory studies reveal far-reaching similarities between classical and phospha-bora-Wittig reactions.
Topics & Concepts
Wittig reactionChemistryLewis acids and basesOrganic chemistryCatalysisOrganophosphorus compounds synthesisPhosphorus compounds and reactionsSynthesis and characterization of novel inorganic/organometallic compounds