Discovery and Heterologous Expression of Microginins from <i>Microcystis aeruginosa</i> LEGE 91341
Nádia Eusébio, Raquel Castelo‐Branco, Diana Sousa, Marco Preto, Paul M. D’Agostino, Tobias A. M. Gulder, Pedro N. Leão
Abstract
BGC is, in fact, responsible for the biosynthesis of microginins and paves the way to accessing new variants from (meta)genome data or through pathway engineering.
Topics & Concepts
Heterologous expressionEscherichia coliBiologyBiosynthesisMicrocystis aeruginosaGene clusterPolyketidePolyketide synthaseBiochemistryRecombineeringMetabolic engineeringGeneGenomeGeneticsComputational biologyBacteriaCyanobacteriaRecombinant DNAMicrobial Natural Products and BiosynthesisMicrobial Metabolism and ApplicationsGenomics and Phylogenetic Studies