Plasma extracellular vesicle phenotyping for the differentiation of early-stage lung cancer and benign lung diseases
Liwen Yuan, Yanpin Chen, Longfeng Ke, Quan Zhou, Jiayou Chen, Min Fan, Alain Wuethrich, Matt Trau, Jing Wang
Abstract
A nanostrategy that combines bright core–shell probes, a nanomixing chip, and machine learning was proposed to evaluate the clinical performance of plasma EV phenotypes in differentiating early-stage lung cancer and benign lung diseases.
Topics & Concepts
Lung cancerStage (stratigraphy)LungExtracellular vesicleExtracellular vesiclesPathologyPhenotypeExtracellularMedicineBiologyInternal medicineCell biologyGeneBiochemistrymicroRNAPaleontologyMicrovesiclesExtracellular vesicles in diseasePhotoacoustic and Ultrasonic ImagingNanoplatforms for cancer theranostics