The diverse role of oral fibroblasts in normal and disease
R. J. Vijayashree, B Sivapathasundharam
Abstract
Fibroblasts are the major cellular component of the connective tissue. They differ both structurally and functionally based on their location. The oral fibroblasts vary from the dermal fibroblasts in their origin, properties and also functions. These cells play an important role in wound healing, tumor progression and metastasis, allergic reactions. In this review, the various functions of the oral fibroblasts are discussed in detail.
Topics & Concepts
Connective tissueFibroblastWound healingMetastasisCancer-Associated FibroblastsCell biologyBiologyCancer researchMedicinePathologyImmunologyCancerCell cultureInternal medicineGeneticsMesenchymal stem cell researchOral health in cancer treatmentOral and gingival health research