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Mechanisms of isoform-specific residue influence on GTP-bound HRas, KRas, and NRas

Alicia Y. Volmar, Hugo Guterres, Hao Zhou, Derion Reid, Spiro Pavlopoulos, Lee Makowski, Carla Mattos

2022Biophysical Journal14 citationsDOIOpen Access PDF

Topics & Concepts

HRASNeuroblastoma RAS viral oncogene homologGene isoformKRASGTPaseGTP'EffectorChemistryBiologyBiochemistryComputational biologyCell biologyMutationEnzymeGeneProtein Kinase Regulation and GTPase SignalingEnzyme Structure and FunctionProtein Structure and Dynamics
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