<i>In Vitro</i> Susceptibilities of Worldwide Isolates of Intrapulmonary <i>Aspergillus</i> Species and Important <i>Candida</i> Species in Sterile Body Sites against Important Antifungals: Data from the Antimicrobial Testing Leadership and Surveillance Program, 2017–2020
Shio-Shin Jean, Hung‐Jen Yang, Po-Chuen Hsieh, Yu‐Tsung Huang, Wen‐Chien Ko, Po‐Ren Hsueh
Abstract
In addition to monitoring the antifungal susceptibilities of clinically important fungi, reviewing the PK/PD indices and the clinical therapy experience of antifungals under evaluation are important to guide an appropriate antifungal prescription. The efficacies of liposomal amphotericin B complex and anidulafungin for the treatment of pulmonary aspergillosis caused by different Aspergillus species need to be periodically evaluated in the future.
Topics & Concepts
Aspergillus fumigatusMicrobiologyCandida dubliniensisAnidulafunginPosaconazoleAspergillus terreusBiologyAspergillusItraconazoleCandida kruseiAmphotericin BBroth microdilutionCandida glabrataCandida albicansAspergillus flavusCaspofunginAntimicrobialCorpus albicansMinimum inhibitory concentrationAntifungalAntifungal resistance and susceptibilityFungal Infections and StudiesAntimicrobial Resistance in Staphylococcus