Serum Antibody Profile of a Patient With Coronavirus Disease 2019 Reinfection
Kelvin Kai‐Wang To, Ivan Fan‐Ngai Hung, Kwok‐Hung Chan, Shuofeng Yuan, Wing‐Kin To, Dominic Ngai‐Chong Tsang, Vincent Chi‐Chung Cheng, Zhiwei Chen, Kin‐Hang Kok, Kwok‐Yung Yuen
Abstract
We recently reported a patient with coronavirus disease 2019 reinfection. Here, we show that serum neutralizing antibodies could be detected during the first episode but not at the presentation of the second episode. During reinfection, neutralizing antibodies and high avidity immunoglobulin G were found within 8 days after hospitalization, whereas immunoglobulin M response was absent.
Topics & Concepts
AntibodyVirologyCoronavirus disease 2019 (COVID-19)CoronavirusDiseaseMedicineImmunologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Infectious disease (medical specialty)Internal medicineSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesSARS-CoV-2 detection and testing