Four-dimensional Flow MRI–based Computational Fluid Dynamics Simulation for Noninvasive Portosystemic Pressure Gradient Assessment in Patients with Cirrhosis and Transjugular Intrahepatic Portosystemic Shunt
Christoph Riedel, Marko Hoffmann, Muhammad Ismahil, Alexander Lenz, Felix Piecha, Inka Ristow, Johannes Kluwe, Michael Schlüter, Gerhard Adam, Bjoern P. Schoennagel, Scott B. Reeder, Peter Bannas
Abstract
< .001). The 4D flow MRI-based CFD simulations correctly classified the presence or absence of a post-TIPS PSPG greater than 12 mm Hg in 16 of 20 participants (80%). Conclusion The combination of 4D flow MRI and CFD was feasible for noninvasive PSPG assessment in participants with cirrhosis, portal hypertension, and TIPS. © RSNA, 2024 See also the editorial by Motosugi and Watanabe in this issue.
Topics & Concepts
MedicineTransjugular intrahepatic portosystemic shuntCirrhosisPortosystemic shuntPortal hypertensionPortal venous pressureRadiologyPressure gradientInternal medicineMechanicsPhysicsLiver Disease and TransplantationLiver Disease Diagnosis and TreatmentAdvanced MRI Techniques and Applications