Recent advances in the synthesis of <i>N</i> -acyl sulfonamides
Michelle O'Driscoll, Gangireddy Sujeevan Reddy, Timothy P. O’Sullivan
Abstract
-acyl sulfonamides are of considerable interest to medicinal chemists. In this review, we summarise developments in the synthesis of this pharmaceutically relevant functional group across a broad range of methodologies.
Topics & Concepts
SulfonamideChemistryCombinatorial chemistryFunctional groupDrug discoveryDrugGroup (periodic table)Chemical synthesisOrganic chemistryStereochemistrySulfur-Based Synthesis TechniquesOrganic and Inorganic Chemical ReactionsSynthesis and Catalytic Reactions