Integrated pseudotime analysis of human pre-implantation embryo single-cell transcriptomes reveals the dynamics of lineage specification
Dimitri Meistermann, Alexandre Bruneau, Sophie Loubersac, Arnaud Reignier, Julie Firmin, Valentin François-Campion, Stéphanie Kilens, Yohann Lelièvre, Jenna Lammers, Magalie Feyeux, Phillipe Hulin, Steven Nédellec, Betty Bretin, Gaël Castel, Nicolas Allègre, Simon Covin, Audrey Bihouée, Magali Soumillon, Tarjei S. Mikkelsen, P. Barrière, Claire Chazaud, Joel Chappell, Vincent Pasque, Jérémie Bourdon, Thomas Fréour, Laurent David
Topics & Concepts
EpiblastBiologyBlastocystTranscriptomeEmbryoInner cell massCell fate determinationLineage (genetic)Cell biologyComputational biologyEndodermGeneticsEmbryogenesisEmbryonic stem cellEvolutionary biologyTranscription factorGeneGastrulationGene expressionSingle-cell and spatial transcriptomicsRNA Research and SplicingPluripotent Stem Cells Research