Optimization of globomycin analogs as novel gram-negative antibiotics
Keira Garland, Homer Pantua, M. Braun, Daniel J. Burdick, Georgette M. Castanedo, Yi‐Chen Chen, Yun‐Xing Cheng, Jonathan Cheong, Blake E. Daniels, Gauri Deshmukh, YuHong Fu, Paul Gibbons, Susan L. Gloor, Rongbao Hua, Sharada S. Labadie, Xiongcai Liu, Richard Pastor, Craig E. Stivala, Min Xu, Yiming Xu, Hao Zheng, Sharookh B. Kapadia, Emily J. Hanan
Topics & Concepts
DepsipeptideAntibioticsNatural productChemistryDrug discoveryAntibacterial activityEscherichia coliIn vivoDrugMicrobiologyLipid IICombinatorial chemistryBacteriaBiochemistryPharmacologyBiologyBiosynthesisEnzymeBiotechnologyGeneGeneticsMicrobial Natural Products and BiosynthesisRNA and protein synthesis mechanismsPeptidase Inhibition and Analysis