Physiologically based pharmacokinetic modelling to predict the pharmacokinetics of metoprolol in different CYP2D6 genotypes
Choong‐Min Lee, Pureum Kang, Chang‐Keun Cho, Hye-Jung Park, Yun Jeong Lee, Jung‐Woo Bae, Chang‐Ik Choi, Hyung Sik Kim, Choon‐Gon Jang, Seok‐Yong Lee
Topics & Concepts
MetoprololPhysiologically based pharmacokinetic modellingCYP2D6PharmacokineticsPharmacologyGenotypePharmacogenomicsPharmacogeneticsChemistryMedicineInternal medicineBiochemistryGenePharmacogenetics and Drug MetabolismAnalytical Methods in PharmaceuticalsStatistical Methods in Clinical Trials