An aldose reductase inhibitor, WJ-39, ameliorates renal tubular injury in diabetic nephropathy by activating PINK1/Parkin signaling
Luxi Yang, Liangting Xu, Xin Hao, Zhixiao Song, Xian Zhang, Peng Liu, Shaojie Wang, Zhonggui He, Libo Zou
Topics & Concepts
Aldose reductasePINK1MitophagyPolyol pathwayParkinMitochondrionDiabetic nephropathyCell biologyBiologyEndocrinologyInternal medicinePharmacologyAutophagyChemistryKidneyBiochemistryApoptosisMedicineDiabetes mellitusParkinson's diseaseDiseaseAldose Reductase and TaurineHeme Oxygenase-1 and Carbon MonoxideAdvanced Glycation End Products research