One-step synthesis of a dual-functional AIE-active probe for ClO<sup>−</sup> detection and photodynamic therapy
Yiping Liu, Juan Fu, Jiaxing Wan, Tongsheng Huang, Weifeng Zhu, Jianwen Tian, Meiying Liu, Xiaoyong Zhang, Yen Wei
Abstract
with fast-response (≤30 s) in aqueous solution and living organisms. Owing to the donor-acceptor (D-A) structure and existence of cationic groups, BHSMP could also generate reactive oxygen species under light-irradiation and potentially be utilized for photodynamic therapy. The strategy described in this work is of great significance for the design and synthesis of multifunctional AIE-active functional materials to facilitate their biomedical applications.
Topics & Concepts
Photodynamic therapyChemistryCombinatorial chemistryDual (grammatical number)RadiochemistryOrganic chemistryLiteratureArtLuminescence and Fluorescent MaterialsMolecular Sensors and Ion DetectionNanoplatforms for cancer theranostics