Net Water Uptake at CT Predicts the Treatment Effect of Thrombectomy for Low ASPECTS Stroke
Gabriel Broocks, Martin Bendszus, Claus Z. Simonsen, Götz Thomalla, Elke R. Gizewski, Anne Hege Aamodt, Antonı́n Krajina, Laurent Pierot, Kamil Zeleňák, Blanca Fuentes, Michael D. Hill, André Kemmling, Susanne Gellißen, Jens Fiehler, Lukas Meyer, Helge Kniep, for the TENSION investigators, Elke R. Gizewski, Astrid Grams, Florian Dazinger, Tanja Janjic, Karin Gindlhuber, Michael Knoflach, Johannes Willeit, Christian Boehme, Stefan Kiechl, Bernhard Glodny, Karoline Volderauer, Lukas Mayer-Süß, Malik Galijašević, Johannes Trenkler, Stephan Meckel, Joachim Gruber, Michael Sonnberger, E Bach, Eva Lenzenweger, Daniel Schwarzenhofer, Hannes Deutschmann, Michael Augustin, Ulrike Wießpeiner, Rupert Horst Portugaller, P. Kalmár, Marton Magyar, Eva Hassler, Thomas Seifert‐Held, Kurt Niederkorn, Thomas Gattringer, Alexander Pichler, Simon Fandler‐Höfler, Siegfried Rohler, Daniela Thaler, Florian Schmid, Susanne Hörner, Monika Killer‐Oberpfalzer, Erasmia Broussalis, Sebastian Mutzenbach, Slaven Pikija, Constantin Hecker, Rahman Al-Schameri, Manuel Lunzer, Michael Kral, Friedrich Weymayr, Nele Bubel, Bernhard Ganser, Ursula Leitner, Floriana Hacker-Ivan, Tobias Moser, Rudolf Kreidenhuber, Asima Delalic, Markus Leitinger, Pfaff Johannes, Kamila Volna, Ferdinand Otto, Matthias Mauritz, Angela Jedlitschka, Michael D. Hill, Mayank Goyal, Karla J. Ryckborst, Antonı́n Krajina, Vendelı́n Chovanec, Jan Raupach, Eva Vítková, Oldřcxch Medek, Ondřej Renc, David Matyáš, Kateřina Vališ, Tomáš Křivka, Igor Suškevič, Jiří Vaníček, Bohuslav Vojtíšek, Robert Mikulík, Stanislava Jakubíček, Ilona Eliášová, Viktor Weiss, David Goldemund, Ondřej Strýček, Jiří Búřil, Michal Haršány, Irena Doležalová, Martin Roubec
Abstract
< .002), suggesting greater treatment efficacy in patients with low NWU. EVT in patients with an NWU of less than 15.0% was associated with a greater probability of achieving an mRS of less than or equal to 3, whereas greater NWU was associated with less effective EVT. Conclusion The degree of NWU at admission CT modified the treatment effect of EVT in patients with large infarct cores. EVT was associated with improved outcomes only in patients with lower NWU, whereas in patients with an NWU of at least 15%, EVT plus BMT did not show a functional benefit over BMT alone. ClinicalTrials.gov Identifier: NCT03094715 © RSNA 2025