Access to <i>gem</i>-Difluoroalkenes via Organic Photoredox-Catalyzed <i>gem</i>-Difluoroallylation of Alkyl Iodides
Songlin Yan, Weijie Yu, Jianye Zhang, Hongmei Fan, Zhi‐Feng Lu, Zhenming Zhang, Tao Wang
Abstract
'-tetramethylethylenediamine as the radical activator of alkyl iodides via halogen-atom transfer. In addition, a variety of iodides, including primary, secondary, and tertiary alkyl iodides, were tolerated and provided good to high yields.
Topics & Concepts
AlkylChemistryHalogenPhotoredox catalysisCatalysisTrifluoromethylPhotocatalysisMedicinal chemistryBond cleavagePrimary (astronomy)Organic chemistryPhotochemistryAstronomyPhysicsFluorine in Organic ChemistryRadical Photochemical ReactionsInorganic Fluorides and Related Compounds