<i>In vivo</i> fermentation production of humanized noncoding RNAs carrying payload miRNAs for targeted anticancer therapy
Peng-Cheng Li, Mei‐Juan Tu, Pui Yan Ho, Neelu Batra, Michelle Tran, Jing-Xin Qiu, Theodore Wun, Primo N. Lara, Xiang Hu, Ai-Xi Yu, Ai‐Ming Yu
Abstract
This novel ncRNA bioengineering technology and resulting recombinant ncRNAs are unique additions to conventional technologies and tools for basic research and drug development.
Topics & Concepts
microRNABiologyNon-coding RNASmall interfering RNARNAIn vivoLong non-coding RNARNA interferenceComputational biologyCancer researchGeneBiotechnologyBiochemistryRNA modifications and cancerRNA Interference and Gene DeliveryBacteriophages and microbial interactions