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Systemic delivery of siRNA to the colon using peptide modified PEG-PCL polymer micelles for the treatment of ulcerative colitis

Hisako Ibaraki, Naruhiro Hatakeyama, Naoki Arima, Akihiro Takeda, Yasuo Seta, Takanori Kanazawa

2021European Journal of Pharmaceutics and Biopharmaceutics21 citationsDOI

Topics & Concepts

MicelleUlcerative colitisPharmacologySmall interfering RNAInflammatory bowel diseaseColitisMedicineSystemic administrationChemistryImmunologyInternal medicineRNAIn vivoBiochemistryDiseaseBiotechnologyGeneBiologyPhysical chemistryAqueous solutionRNA Interference and Gene DeliveryInflammatory Bowel DiseaseViral gastroenteritis research and epidemiology
Systemic delivery of siRNA to the colon using peptide modified PEG-PCL polymer micelles for the treatment of ulcerative colitis | Litcius