Zirconium-catalysed direct substitution of alcohols: enhancing the selectivity by kinetic analysis
Cristiana Margarita, Piret Villo, Hernando Tuñon, Oscar Dalla-Santa, David Camaj, Robin Carlsson, Malin Lill, Anja Ramström, Helena Lundberg
Abstract
Kinetic analysis was used as a tool for rational optimization of catalytic direct substitution of alcohols to enable selective formation of ethers, thioethers, and Friedel–Crafts alkylation products using a moisture-tolerant and commercially available Zr complex.
Topics & Concepts
Substitution (logic)SelectivityAlkylationChemistryZirconiumCatalysisKinetic energySubstitution reactionOrganic chemistryCombinatorial chemistryComputer sciencePhysicsQuantum mechanicsProgramming languageAsymmetric Hydrogenation and CatalysisChemical Synthesis and ReactionsChemical Synthesis and Analysis