Synthesis and biological evaluation of isatin oxime ether-tethered aryl 1<i>H</i>-1,2,3-triazoles as inhibitors of<i>Mycobacterium tuberculosis</i>
Sampath Kumar Kancharla, Saritha Birudaraju, Arani Pal, L. Krishnakanth Reddy, Eda Rami Reddy, Siva Krishna Vagolu, Dharmarajan Sriram, Kishore Babu Bonige, Raghu Babu Korupolu
Abstract
A series of isatin oxime ether-tethered aryl 1 H -1,2,3-triazole hybrids were synthesized and screened for their in vitro antitubercular activity against the M. tuberculosis H37Rv strain.
Topics & Concepts
IsatinChemistryArylEtherOximeMycobacterium tuberculosisStereochemistryIn vitroTriazoleCombinatorial chemistryTuberculosisOrganic chemistryBiochemistryAlkylPathologyMedicineClick Chemistry and ApplicationsSynthesis and Biological EvaluationSynthesis and biological activity