Aerobic oxidation of primary benzylic amines to amides and nitriles catalyzed by ruthenium carbonyl clusters carrying N,O-bidentate ligands
Xinlong Yan, Qing Dong, Ying Li, Li-zhen Meng, Zhiqiang Hao, Zhangang Han, Guo‐Liang Lu, Jin Lin
Abstract
with the corresponding N,O-bidentate ligands (two pyridyl alcohols and two Schiff bases) respectively in a ratio of 1 : 2. Three new complexes 1b, 2a and 2b have been fully characterized by elemental analysis, FT-IR, NMR and X-ray crystallography. The catalytic activity of these ruthenium complexes for the aerobic oxidation of primary benzylic amines to amides and nitriles in the presence of t-BuOK was investigated, of which the Schiff base complex 2a was found to exhibit the highest activity.
Topics & Concepts
DenticityRutheniumCatalysisChemistryPrimary (astronomy)SelectivityMedicinal chemistryCombinatorial chemistryOrganic chemistryMetalPhysicsAstronomyChemical Synthesis and AnalysisAsymmetric Hydrogenation and CatalysisSynthesis and Catalytic Reactions