Loss of Sirt1 promotes exosome secretion from podocytes by inhibiting lysosomal acidification in diabetic nephropathy
Lin Ding, Zuo-lin Li, Yan Zhou, Nan-chi Liu, Shan-Shan Liu, Xingjian Zhang, Congcong Liu, Dongjie Zhang, Guihua Wang, Ruixia Ma
Topics & Concepts
PodocyteMicrovesiclesSecretionExosomeCell biologyDiabetic nephropathyInternal medicineAutophagyChemistryEndocrinologyDownregulation and upregulationBiologyKidneyBiochemistrymicroRNAApoptosisMedicineProteinuriaGeneExtracellular vesicles in diseaseRenal Diseases and GlomerulopathiesAutophagy in Disease and Therapy