Pd-Catalyzed Etherification of Nitroarenes
Naoki Matsushita, Myuto Kashihara, Michele Formica, Yoshiaki Nakao
Abstract
The Pd-catalyzed etherification of nitroarenes with arenols has been achieved using a new rationally designed ligand. Mechanistic insights were used to design the ligand so that both the oxidative addition and reductive elimination steps of a plausible catalytic cycle were facilitated. The catalytic system established here provides direct access to a range of unsymmetrical diaryl ethers from nitroarenes.
Topics & Concepts
ChemistryCatalysisCatalytic cycleLigand (biochemistry)Reductive eliminationCombinatorial chemistryOxidative phosphorylationOxidative additionOrganic chemistryReceptorBiochemistryNanomaterials for catalytic reactionsCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling Reactions