Overview of Coumarins and its Derivatives: Synthesis and Biological Activity
Tanvi Sahni, Sunita Sharma, Diksha Verma, Pardeep Kaur
Abstract
Coumarin is a heterocyclic scaffold and its derivatives, namely Schiff bases, esters, and hydrazides, etc., play an important role in the field of agrochemical and pharmaceutical industry due to its structure. Over the years, various biological activities like antifungal, antimicrobial, antiviral, anti-cancerous, anti-tumor, anti-inflammatory, anti-filarial, enzyme inhibitors, antiaflatoxigenic, analgesics, antioxidant and Oestrogenic, etc., have been analyzed. This review covers the latest literature and knowledge on the synthetic procedures for various coumarin and its derivatives, their biological and pharmacological applications.
Topics & Concepts
CoumarinChemistryAntifungalAntimicrobialBiological activityCombinatorial chemistryAgrochemicalOrganic chemistryBiochemistryIn vitroMicrobiologyAgricultureBiologyEcologyInorganic and Organometallic ChemistrySynthesis and biological activity