GRK2 participation in cardiac hypertrophy induced by isoproterenol through the regulation of Nrf2 signaling and the promotion of NLRP3 inflammasome and oxidative stress
Jing Liu, Xiaoli Li, Lu Ding, Wei Li, Xiaolin Niu, Dengfeng Gao
Topics & Concepts
Beta adrenergic receptor kinaseOxidative stressChemistrySmall interfering RNAPharmacologyKinaseSignal transductionViability assayInternal medicineEndocrinologyApoptosisMolecular biologyBiologyBiochemistryMedicineTransfectionG protein-coupled receptorGeneInflammasome and immune disordersEndoplasmic Reticulum Stress and DiseaseIon Channels and Receptors