An injectable serotonin–chondroitin sulfate hydrogel for bio-inspired hemostatic adhesives with high wound healing capability
Xingxia Zhang, Zhifang Ma, Yue Ke, Yu Xia, Xiaodong Xu, Jingchuan Liu, Yumei Gong, Qiang Shi, Jinghua Yin
Abstract
An injectable hydrogel inspired by platelet clotting mediators is developed based on natural components of the human body including serotonin and chondroitin sulfate, which exhibits improved hemostatic performance and wound healing capability.
Topics & Concepts
Wound healingChondroitin sulfateAdhesiveBlood clottingHemostatic AgentSerotoninHeparinPlateletChemistryHemostasisBiomedical engineeringMaterials scienceMedicineNanotechnologySurgeryBiochemistryGlycosaminoglycanInternal medicineReceptorLayer (electronics)Surgical Sutures and AdhesivesHemostasis and retained surgical itemsWound Healing and Treatments