Nitric oxide inhalation as an interventional rescue therapy for COVID-19-induced acute respiratory distress syndrome
Jun Kobayashi, Isamu Murata
Abstract
COVID-19 is an emerging disease of public health concern. While there is no specific recommended treatment for COVID-19, nitric oxide has the potential to be of therapeutic value for managing acute respiratory distress syndrome in patients with COVID-19. However, inhaled nitric oxide has not yet been formally evaluated. Given the extent of the COVID-19 pandemic, and the large numbers of hospitalized patients requiring respiratory support, clinical use of inhaled nitric oxide may become an alternate rescue therapy before extracorporeal membrane oxygenation for the management of acute respiratory distress syndrome in patients with COVID-19.
Topics & Concepts
MedicineExtracorporeal membrane oxygenationNitric oxideAcute respiratory distressCoronavirus disease 2019 (COVID-19)Intensive care medicineRespiratory distressAnesthesiologyInhalationAnesthesiaRespiratory systemDiseaseInternal medicineLungInfectious disease (medical specialty)Respiratory Support and MechanismsLong-Term Effects of COVID-19Cardiac Arrest and Resuscitation