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Effects of Low-Level Light Therapy on Resting-State Connectivity Following Moderate Traumatic Brain Injury: Secondary Analyses of a Double-blinded Placebo-controlled Study

Suk‐Tak Chan, Nathaniel D. Mercaldo, Maria Gabriela Figueiró Longo, Jonathan Welt, Arman Avesta, Jarone Lee, Michael H. Lev, Eva‐Maria Ratai, Michael Wenke, Blair A. Parry, Lynn A. Drake, Richard R. Anderson, Terry M. Rauch, Ramon Diaz‐Arrastia, Kenneth K. Kwong, Michael R. Hamblin, Benjamin J. Vakoc, Rajiv Gupta

2024Radiology13 citationsDOIOpen Access PDF

Abstract

value range, .44-.99), as measured according to RPQ scores. Conclusion Despite the small sample size, the change in RSFC from the acute to subacute phases of recovery was greater in LLLT-treated than sham-treated participants, suggesting that acute-phase LLLT may have an impact on resting-state neuronal circuits in the early recovery phase of moderate TBI. ClinicalTrials.gov Identifier: NCT02233413 © RSNA, 2024

Topics & Concepts

MedicineTraumatic brain injuryPlaceboResting state fMRIDouble blindedPhysical therapyAnesthesiaPhysical medicine and rehabilitationPsychiatryRadiologyPathologyAlternative medicineFunctional Brain Connectivity StudiesTraumatic Brain Injury ResearchOptical Imaging and Spectroscopy Techniques
Effects of Low-Level Light Therapy on Resting-State Connectivity Following Moderate Traumatic Brain Injury: Secondary Analyses of a Double-blinded Placebo-controlled Study | Litcius