Platelet-rich plasma-derived extracellular vesicles inhibit NF-κB/NLRP3 pathway-mediated pyroptosis in intervertebral disc degeneration via the MALAT1/microRNA-217/SIRT1 axis
Xueqiang Tao, Fen Xue, Jiayuan Xu, Wenbo Wang
Topics & Concepts
Downregulation and upregulationCell biologyPyroptosisChemistryMALAT1microRNAExtracellular matrixApoptosisExosomeProgrammed cell deathMolecular biologyMicrovesiclesBiologyBiochemistryLong non-coding RNAGeneSpine and Intervertebral Disc PathologyTendon Structure and TreatmentPain Mechanisms and Treatments