An anthracenecarboximide-guanidine fluorescent probe for selective detection of glyoxals under weak acidic conditions
Junwei Chen, Yuna Lin, Wanjin Xing, Xingchen Zhang, Huan Xu, Wei Wang, Kaiyan Lou
Abstract
An anthracenecarboximide-guanidine based turn-on fluorescent probe ANC-DCP-1 for selective detection of glyoxals (methylglyoxal and glyoxal, GOS) over formaldehyde under weak acidic conditions around pH 6.0 was reported. The probe showed great potential in studying relative GOS levels in weak acidic biological fluids such as in urine for diabetic diagnosis and prognosis, and also found application in the food industry such as for fast unique manuka factor (UMF) scale determination of Manuka honey.
Topics & Concepts
MethylglyoxalGlyoxalChemistryGuanidineFluorescenceFormaldehydeChromatographyCombinatorial chemistryOrganic chemistryEnzymeQuantum mechanicsPhysicsAdvanced Glycation End Products researchBiochemical effects in animalsBee Products Chemical Analysis