Visible Light-Promoted Radical-Mediated Ring-Opening/Cyclization of Vinyl Benzotriazoles: An Alternative Approach to Phenanthridines
Jia‐Qi Li, Shichong Wang, Jingjing Zhao, Pan Li
Abstract
A visible light-promoted radical-mediated ring-opening/cyclization of vinyl benzotriazoles has been developed. The method provides an efficient and practical approach to synthesize functionalized phenanthridines from vinyl benzotriazoles with alkyl bromides under mild conditions. Significantly, the readily available and bench-stable vinyl benzotriazoles can serve as valuable alternative radical acceptors during the synthesis of phenanthridines.
Topics & Concepts
ChemistryRing (chemistry)AlkylCombinatorial chemistryRadical cyclizationOrganic chemistryPhotochemistryRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques