Albumin–manganese dioxide nanocomposites: a potent inhibitor and ROS scavenger against Alzheimer's β-amyloid fibrillogenesis and neuroinflammation
Weiqun Gao, Wei Liu, Xiaoyan Dong, Yan Sun
Abstract
studies showed that HMn NCs could remove Aβ plaques, reduce ROS in CL2006 worms, and promote the lifespan extension of worms. Thus, HMn NCs provide a promising tactic to facilitate the application of multifunctional nanocomposites in AD treatment.
Topics & Concepts
FibrillogenesisScavengerManganeseNeuroinflammationAlbuminAmyloid (mycology)NanocompositeChemistryTranslocator proteinMaterials scienceBiophysicsNuclear chemistryBiochemistryMedicineOrganic chemistryFibrilNanotechnologyInorganic chemistryInternal medicineInflammationBiologyRadicalAlzheimer's disease research and treatmentsAdvanced Nanomaterials in CatalysisNanoparticle-Based Drug Delivery