The alkaloid, soyauxinium chloride, displays remarkable cytotoxic effects towards a panel of cancer cells, inducing apoptosis, ferroptosis and necroptosis
Armelle T. Mbaveng, Cédric Guy Tchatchouang Noulala, Anne R.M. Samba, Simplice B. Tankeo, Sara Abdelfatah, Ghislain W. Fotso, Emmanuel Ngeufa Happi, Bonaventure T. Ngadjui, Véronique Penlap Beng, Victor Kuete, Thomas Efferth
Topics & Concepts
NecroptosisCytotoxic T cellApoptosisProgrammed cell deathCancer cellCytotoxicityAnnexinCancer researchCell cultureJurkat cellsChemistryCaspaseBiologyMolecular biologyCancerBiochemistryImmunologyIn vitroT cellImmune systemGeneticsCancer therapeutics and mechanismsQuinazolinone synthesis and applicationsSynthesis and bioactivity of alkaloids