Effect of antioxidants on the H2O2-induced premature senescence of human fibroblasts
Natalia Pieńkowska, Grzegorz Bartosz, Monika Pichla, Michalina Grzesik, Martyna Gruchala, Izabela Sadowska‐Bartosz
Abstract
and suggest that the small protective action of antioxidants is due to their effects on mitochondria.
Topics & Concepts
Oxidative stressFibroblastAntioxidantSenescenceMitochondrionChemistryGlutathioneCell cultureBiochemistryHydrogen peroxidePremature agingMolecular biologyCell biologyIn vitroBiologyGeneticsEnzymeTelomeres, Telomerase, and SenescenceMitochondrial Function and PathologyRedox biology and oxidative stress