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FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome

Fuming Li, Peiwei Huangyang, Michelle Burrows, Kathy Guo, Romain Riscal, Jason T. Godfrey, Kyoung Eun Lee, Nan Lin, Pearl Lee, Ian A. Blair, Brian Keith, Bo Li, M. Celeste Simon

2020Nature Cell Biology205 citationsDOIOpen Access PDF

Topics & Concepts

HepatocyteSenescenceHepatic stellate cellBiologyCarcinogenesisCell biologySteatosisAutophagyCrosstalkCancer researchEndocrinologyCancerBiochemistryApoptosisIn vitroOpticsPhysicsGeneticsCancer, Hypoxia, and MetabolismLiver Disease Diagnosis and TreatmentCancer-related Molecular Pathways
FBP1 loss disrupts liver metabolism and promotes tumorigenesis through a hepatic stellate cell senescence secretome | Litcius