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In vitro biological and in silico molecular docking and ADME studies of a substituted triazine-coordinated cadmium(II) ion: efficient cytotoxicity, apoptosis, genotoxicity, and nuclease-like activity plus binding affinity towards apoptosis-related proteins

Marzieh Anjomshoa, Mehdi Sahihi, S. Jamilaldin Fatemi, Shika Shayegan, Alireza Farsinejad, Bagher Amirheidari

2022BioMetals15 citationsDOIOpen Access PDF

Topics & Concepts

CytotoxicityApoptosisComet assayMTT assayDNA fragmentationApoptotic DNA fragmentationChemistryDNA damageMolecular biologyProgrammed cell deathGenotoxicityBiochemistryBiologyDNAIn vitroToxicityOrganic chemistrySynthesis and Characterization of Heterocyclic CompoundsMetal complexes synthesis and propertiesClick Chemistry and Applications
In vitro biological and in silico molecular docking and ADME studies of a substituted triazine-coordinated cadmium(II) ion: efficient cytotoxicity, apoptosis, genotoxicity, and nuclease-like activity plus binding affinity towards apoptosis-related proteins | Litcius