Enhancing FRET biosensing beyond 10 nm with photon avalanche nanoparticles
Artur Bednarkiewicz, Emory M. Chan, Katarzyna Prorok
Abstract
10-25 nm) than those typically found in conventional FRET systems. This promises high sensitivity, low background and spectral or temporal biosensing, and provides the basis for a radically novel approach to combine luminescence imaging and self-normalized bio-molecular interaction sensing.
Topics & Concepts
BiosensorFörster resonance energy transferNanotechnologyNanoparticleMaterials scienceTwo-photon excitation microscopyAvalanche photodiodeOptoelectronicsFluorescenceOpticsPhysicsDetectorNanoplatforms for cancer theranosticsLuminescence Properties of Advanced MaterialsLuminescence and Fluorescent Materials