HSC-derived exosomal miR-199a-5p promotes HSC activation and hepatocyte EMT via targeting SIRT1 in hepatic fibrosis
Hongjian Lu, Rong‐Hua Zhang, Shukun Zhang, Yufeng Li, Yankun Liu, Yanan Xiong, Xiaohan Yu, Tao Lan, Xin Li, Meimei Wang, Zhiyong Liu, Guangling Zhang, Xin Li, Shuang Chen, Zhiyong Liu, Guangling Zhang, Jingwu Li, Shuang Chen
Topics & Concepts
Downregulation and upregulationHepatic stellate cellChemistryFibrosisHepatocyteCholestasisHepatic fibrosismicroRNACancer researchEpithelial–mesenchymal transitionEctopic expressionCell growthCell biologyBiologyInternal medicineEndocrinologyMedicineBiochemistryIn vitroGeneExtracellular vesicles in diseaseMicroRNA in disease regulationCircular RNAs in diseases