Litcius/Paper detail

Can the personalized medicine approach contribute in controlling tuberculosis in general and India in particular?

Nikhat Khan, Aparup Das

2020Precision Clinical Medicine14 citationsDOIOpen Access PDF

Abstract

Abstract Poor drug compliance and drug-resistant Mycobacterium tuberculosis are the two principal obstacles in controlling tuberculosis (TB) in endemic regions including India, which has contributed the most to global TB burden. We argue here that a personalized medicine approach, to start with the N-acetyl transferase-2–isoniazid (NAT2–INH) model, could be a step forward in dealing with both these limitations in controlling TB in India.

Topics & Concepts

TuberculosisIsoniazidPersonalized medicineMycobacterium tuberculosisMedicinePrincipal (computer security)Precision medicineIntensive care medicineTraditional medicineBiologyBioinformaticsPathologyComputer scienceOperating systemTuberculosis Research and EpidemiologyPneumocystis jirovecii pneumonia detection and treatmentBiochemical and Molecular Research