Cortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog
Yue Zhang, Guoping Liu, Teng Guo, Xiaoyi G. Liang, Heng Du, Lin Yang, Aparna Bhaduri, Xiaosu Li, Zhejun Xu, Zhuangzhi Zhang, Zhenmeiyu Li, Miao He, Jeremiah Tsyporin, Arnold R. Kriegstein, John L.R. Rubenstein, Zhengang Yang, Bin Chen
Abstract
IPCs and the process of the lineage switch of cortical NSCs.
Topics & Concepts
Sonic hedgehogNeural stem cellBiologyOlfactory bulbNeocortexProgenitor cellNeurosciencePopulationProgenitorHedgehog signaling pathwayGlutamatergicNeurosphereStem cellCell biologyCellular differentiationSignal transductionAdult stem cellGeneticsCentral nervous systemGeneGlutamate receptorSociologyReceptorDemographyNeurogenesis and neuroplasticity mechanismsMicroRNA in disease regulationCancer-related molecular mechanisms research