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Predicting Drug Interactions with Human Equilibrative Nucleoside Transporters 1 and 2 Using Functional Knockout Cell Lines and Bayesian Modeling

Siennah R. Miller, Xiaohong Zhang, Raymond K. Hau, Joseph L. Jilek, Erin Q. Jennings, James J. Galligan, Daniel H. Foil, Kimberley M. Zorn, Sean Ekins, Stephen H. Wright, Nathan J. Cherrington

2020Molecular Pharmacology23 citationsDOIOpen Access PDF

Topics & Concepts

UridineNucleosideCytidineGene knockoutBiologyBiochemistryChemistryPharmacologyRNAEnzymeGeneHIV/AIDS drug development and treatmentHIV Research and TreatmentPharmacological Effects and Toxicity Studies
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