Celastrol nanoemulsion induces immunogenicity and downregulates PD-L1 to boost abscopal effect in melanoma therapy
Nasha Qiu, Yun Liu, Qi Liu, Yanzuo Chen, Limei Shen, Mengying Hu, Xuefei Zhou, Youqing Shen, Jianqing Gao, Leaf Huang
Topics & Concepts
ImmunogenicityCelastrolAbscopal effectMelanomaImmunotherapyMaterials scienceCancer researchMedicineImmune systemImmunologyApoptosisBiologyBiochemistryNatural Compounds in Disease TreatmentImmunotherapy and Immune ResponsesNanoparticle-Based Drug Delivery