Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea
Robert M. Bowers, Nikos C. Kyrpides, Ramūnas Stepanauskas, Miranda Harmon‐Smith, Devin F. R. Doud, T. B. K. Reddy, Frederik Schulz, Jessica K. Jarett, Adam R. Rivers, Emiley A. Eloe‐Fadrosh, Susannah G. Tringe, Natalia Ivanova, Alex Copeland, Alicia Clum, Eric D. Becraft, Rex R. Malmstrom, Bruce W. Birren, Mircea Podar, Peer Bork, George M. Weinstock, George M Garrity, Jeremy A. Dodsworth, Shibu Yooseph, Granger Sutton, Frank Oliver Glöckner, Jack A. Gilbert, William Nelson, Steven Hallam, Sean P. Jungbluth, Thijs J. G. Ettema, Scott Tighe, Konstantinos T. Konstantinidis, Wen‐Tso Liu, Brett J. Baker, Thomas Rattei, Jonathan A. Eisen, Brian P. Hedlund, Katherine D. McMahon, Noah Fierer, Rob Knight, ROBERT FINN, Guy Cochrane, Ilene Karsch‐Mizrachi, Gene W Tyson, Christian Rinke, Alla Lapidus, Folker Meyer, Pelin Yilmaz, Donovan H. Parks, A. Murat Eren, Lynn M. Schriml, Jillian F. Banfield, Philip Hugenholtz, Tanja Woyke
Abstract
We present two standards developed by the Genomic Standards Consortium (GSC) for reporting bacterial and archaeal genome sequences. Both are extensions of the Minimum Information about Any (x) Sequence (MIxS). The standards are the Minimum Information about a Single Amplified Genome (MISAG) and the Minimum Information about a Metagenome-Assembled Genome (MIMAG), including, but not limited to, assembly quality, and estimates of genome completeness and contamination. These standards can be used in combination with other GSC checklists, including the Minimum Information about a Genome Sequence (MIGS), Minimum Information about a Metagenomic Sequence (MIMS), and Minimum Information about a Marker Gene Sequence (MIMARKS). Community-wide adoption of MISAG and MIMAG will facilitate more robust comparative genomic analyses of bacterial and archaeal diversity.