Cholesterol inhibits TCR signaling by directly restricting TCR-CD3 core tunnel motility
Yan Chen, Yuwei Zhu, Xiang Li, Wenbo Gao, Ziqi Zhen, De Dong, Buliao Huang, Zhuo Ma, Anqi Zhang, Xiaocui Song, Yan Ma, Changyou Guo, Fan Zhang, Zhiwei Huang
Topics & Concepts
T-cell receptorBiologyCD3Cell biologyCholesterolTransmembrane proteinBiochemistryReceptorT cellAntigenImmune systemImmunologyCD8Immune Cell Function and InteractionT-cell and B-cell ImmunologyReceptor Mechanisms and Signaling