Cryo-EM Structure of the Prostaglandin E Receptor EP4 Coupled to G Protein
Shingo Nojima, Yoko Fujita, Kanako Kimura, Norimichi Nomura, Ryoji Suno, Kazushi Morimoto, Masaki Yamamoto, Takeshi Noda, So Iwata, Hideki Shigematsu, Takuya Kobayashi
Topics & Concepts
G protein-coupled receptorProstanoidTransmembrane domainReceptorHeterotrimeric G proteinG proteinProstaglandinChemistryProtein structureHelix (gastropod)BiologyCell biologyBiochemistrySnailEcologyReceptor Mechanisms and SignalingLipid Membrane Structure and BehaviorRNA and protein synthesis mechanisms