Nuclear IL-33 Plays an Important Role in IL-31‒Mediated Downregulation of FLG, Keratin 1, and Keratin 10 by Regulating Signal Transducer and Activator of Transcription 3 Activation in Human Keratinocytes
Xiuju Dai, Ken Shiraishi, Jun Muto, Ryo Utsunomiya, Hideki Mori, Masamoto Murakami, Koji Sayama
Topics & Concepts
STAT3STAT proteinTranscription factorKeratin 5STAT6BiologyCell biologyCytokineDownregulation and upregulationPhosphorylationInvolucrinSignal transductionKeratinCellular differentiationMolecular biologyImmunologyInterleukin 4GeneGeneticsDermatology and Skin DiseasesIL-33, ST2, and ILC PathwaysTransgenic Plants and Applications