Synthesis, in vitro anticancer activity and in silico studies of certain isoxazole-based carboxamides, ureates, and hydrazones as potential inhibitors of VEGFR2
Sahar M. Abou‐Seri, Amal A.M. Eissa, Mohamed G.M. Behery, Farghaly A. Omar
Topics & Concepts
ChemistryIsoxazoleIn vitroCytotoxicityIC50Growth inhibitionStereochemistrySorafenibIn silicoPharmacologyCell cultureCombinatorial chemistryHepatocellular carcinomaCancer researchBiochemistryGeneticsBiologyGeneMedicineSynthesis and biological activityCancer Mechanisms and TherapyBioactive Compounds and Antitumor Agents