Bufotalin induces ferroptosis in non-small cell lung cancer cells by facilitating the ubiquitination and degradation of GPX4
Wen Zhang, Baoping Jiang, Yunxin Liu, Li Xu, Meng Wan
Topics & Concepts
GPX4A549 cellLipid peroxidationCancer cellCell biologyChemistryProgrammed cell deathReactive oxygen speciesIntracellularCancer researchCellGlutathioneBiologyBiochemistryCancerGlutathione peroxidaseApoptosisOxidative stressEnzymeGeneticsFerroptosis and cancer prognosisCancer, Lipids, and MetabolismRNA modifications and cancer