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Case Report: High-dose steroid and IVIG successful treatment in a case of COVID-19-associated autoimmune encephalitis: a literature review

Chi‐Hung Liu, Li‐Chung Chiu, Chih-Chun Lee, Tien‐Ming Chan

2023Frontiers in Immunology10 citationsDOIOpen Access PDF

Abstract

Autoimmune encephalitis is a rare but critical complication of COVID-19. The management of COVID-19-associated autoimmune encephalitis includes the use of steroids, intravenous immunoglobulin (IVIG), plasmapheresis, and monoclonal antibody therapy. This study presented a patient with critical COVID-19 autoimmune encephalitis who rapidly recovered after the initiation of corticosteroids and IVIG therapy. This study reviewed the current literature on the pathophysiological mechanisms, diagnosis, and management of COVID-19-associated autoimmune encephalitis.

Topics & Concepts

Autoimmune encephalitisPlasmapheresisMedicineEncephalitisCoronavirus disease 2019 (COVID-19)ImmunologyIntravenous Immunoglobulin TherapyAntibodyComplicationVirusDiseasePathologyInternal medicineInfectious disease (medical specialty)Autoimmune Neurological Disorders and TreatmentsLong-Term Effects of COVID-19Peripheral Neuropathies and Disorders